When a Jehovah’s Witness With AML Refuses Blood Transfusions
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The refusal of blood transfusions by Jehovah’s Witnesses poses a major challenge in treating acute myeloid leukaemia (AML), particularly in patients presenting with severe anaemia.
A woman in her late twenties, presented with a haemoglobin of 6.7 g/dL, received azacitidine and venetoclax, but her haemoglobin fell to 3.7 g/dL during therapy. Despite completing three outpatient courses of azacitidine monotherapy, the patient continued to decline in blood products and died at home.
A case report by Rida Altaf, DO, and colleagues from the Department of Internal Medicine, Orlando Regional Healthcare System, Orlando, Florida, highlighted the clinical complexity of AML management without transfusions and underscored the need for alternative therapies and haematologic support strategies.
Read more https://www.medscape.com/viewarticle/when-jehovahs-witness-aml-refuses-blood-transfusions-2025a1000sd5?form=fpf
Content retrieved from: https://www.medscape.com/viewarticle/when-jehovahs-witness-aml-refuses-blood-transfusions-2025a1000sd5?form=fpf.
